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SA-557

N-2-Hydroxyethylnicotinamide, 98%

CAS No. : 
[6265-73-2]    
MDL No. : 
MFCD00547113
Synonyms : N-(2-hydroxyethyl)pyridine-3-carboxamide; Nicorandil EP impurity B

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
1G200.00 In Stock Available to Ship on 11.28.2024
5G800.00 In Stock Available to Ship on 11.28.2024
Chemical Properties
C8H10N2O2 166.18
Pale yellow solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : N-2-Hydroxyethylnicotinamide is an impurity of Nicorandil (Nicorandil EP impurity B), which is a potassium channel activator, and stimulates guanylate cyclase to increase formation of cyclic GMP (cGMP), used to treat angina.
References : Sato T. et al. J. Am. Coll. Cardiol., 35(2), 514-518, 2000; Akao M.et al.: J. Am. Coll. Cardiol., 40(4), 803-810, 2002; Szczepanik A. M. et al.: J. Pharmacol Exp Ther., 278(2), 913-920, 1996; Teshima Y. et al.: Brain Res., 990(1-2), 45-50, 2003; Sathish V. et al.: Mol Cell Biochem., 243(1-2), 133-138, 2003.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SA-557

Product Name : N-2-Hydroxyethylnicotinamide

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