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SL-2479

Apremilast EP impurity F, 98%

Synonyms : 2-Amino-6-((1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)carbamoyl)benzoic acid; rac-N-Deacetyl-2-carboxy-(seco-phthalimido) apremilast

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG280.00 Back Order Estimated to Ship on 12.24.2024
10MG400.00 Back Order Estimated to Ship on 12.24.2024
25MG850.00 Back Order Estimated to Ship on 12.24.2024
Chemical Properties
C20H24N2O7S 436.48
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : 2-Amino-6-((1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)carbamoyl)benzoic acid is an impurity of Apremilast (Apremilast EP impurity F). A novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors. Apremilast inhibits PDE4 with an IC50 of 74 nM using 1 μM cAMP as substrate.
References : Perez-Aso M. et al.: Arthritis Res Ther.,17, 249, 2015; Chen L.G. et al.: J. Chromatogr Sci. 54 (8), 1336-40, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2479

Product Name : Apremilast EP impurity F

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