SynInnova Laboratories Inc.

SI-1065

Ruxolitinib, >98% (HPLC)

CAS No. :

[941678-49-5]

MDL No. :

MFCD12031592

Synonyms : (R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile; INCB018424

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 01.14.2025
25MG	Request Quote	- +	Back Order	Estimated to Ship on 01.14.2025
100MG	Request Quote	- +	Back Order	Estimated to Ship on 01.14.2025

Note: Ruxolitinib is not in stock, can be available through custom synthesis. The estimated lead-time is 8-10 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
Mol. Formula : C₁₇H₁₈N₆	Mol. Weight : 306.37
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ruxolitinib is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3.

References : Quintas-Cardama A. et al. Blood, 115 (15), 3109-3117, 2010; Verstovsek S. et al. N. Engl. J. Med., 366 (9), 799-807, 2012; Harrison C. et al. N. Engl. J. Med., 366 (9):787-798, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

To receive price and delivery information on larger quantities, please complete the form below and we will respond promptly.

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Your request for quote will also be accepted by e-mail at sales@syninnova.com or Fax: +1 780 485 2963.

Product ID : SI-1065

Product Name : Ruxolitinib

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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SI-1065

Ruxolitinib, >98% (HPLC)

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