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SI-1512

Isavuconazonium sulfate, 98% (HPLC)

CAS No. : 
[946075-13-4]    
Synonyms : Isavuconazole; Cresemba; BAL8557; BAL-8557

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MGRequest QuoteBack Order Estimated to Ship on 12.22.2024
25MGRequest QuoteBack Order Estimated to Ship on 12.22.2024
100MGRequest QuoteBack Order Estimated to Ship on 12.22.2024

SI-1512 is not in stock, can be available through custom synthesis. The estimated lead-time is 8-10 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
C35H35F2N8O5S+ . HSO4 - 814.84
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Isavuconazonium sulfate is a water-soluble prodrug, which is rapidly hydrolyzed by esterases (mainly butylcholinesterase) in plasma into the active moiety Isavuconazole (BAL-4815) and an inactive cleavage product (BAL-8728). Isavuconazole inhibits cytochrome P450 (CYP)-dependent enzyme lanosterol 14-ademethylase (CYP51) and thereby inhibits the synthesis of ergosterol, a key component of the fungal cell membrane. Isavuconazole displayed potent fungistatic or fungicidal activity in vitro against a broad range of clinically important yeasts and molds.
References : Flick C. A. et al.: J. Med. Chem., 60, 6480-6515, 2017.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-1512

Product Name : Isavuconazonium sulfate

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