SynInnova Laboratories Inc.

SI-1781

Bimiralisib, 98% (HPLC)

CAS No. :

[1225037-39-7]

MDL No. :

MFCD28902193

Synonyms : 5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl) pyridin-2-amine; PQR309

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	80.00	- +	Back Order	Estimated to Ship on 11.30.2024
25MG	220.00	- +	Back Order	Estimated to Ship on 11.30.2024
50MG	380.00	- +	Back Order	Estimated to Ship on 11.30.2024
100MG	580.00	- +	Back Order	Estimated to Ship on 11.30.2024
250MG	980.00	- +	Back Order	Estimated to Ship on 11.30.2024

Chemical Properties
Mol. Formula : C₁₇H₂₀F₃N₇O₂	Mol. Weight : 411.38
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Bimiralisib is a potent, brain-penetrant, orally bioavailable, pan-class I PI3K/mTOR inhibitor with IC50s of 33 nM, 451 nM, 661 nM, 708 nM and 89 nM for PI3Kα, PI3Kδ, PI3Kβ, PI3Kγ and mTOR, respectively. PQR309 is an mTORC1 and mTORC2 inhibitor.

References : Beaufils F. et al.: J Med Chem., 60, 7524-7538, 2017; Tarantelli C. et al.: Clin Cancer Res., 24 (1), 120-129, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-1781

Product Name : Bimiralisib

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SI-1781

Bimiralisib, 98% (HPLC)

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