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SI-2177

3-Chloro-4-(((3R,7S)-7-((4-chlorophenyl)thio)-1-oxa-5-azaspiro[2.4]heptan-5-yl)sulfonyl)benzonitrile, 97%


Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
1GRequest QuoteBack Order Estimated to Ship on 01.17.2025
5GRequest QuoteBack Order Estimated to Ship on 01.17.2025
Chemical Properties
C18H14Cl2N2O3S2 441.35
White solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : This is an advanced key intermediate in the preparation of SI-2174 and related analogs, which is a transient receptor potential vanilloid‑4 (TRPV4) antagonist to treat pulmonary edema of heart failure patients.
References : Pero E. J. et al.: J. Med. Chem., 61(24),11209-11220, 2018.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-2177

Product Name : 3-Chloro-4-(((3R,7S)-7-((4-chlorophenyl)thio)-1-oxa-5-azaspiro[2.4]heptan-5-yl)sulfonyl)benzonitrile

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