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SI-2651

Entrectinib, >98% (HPLC)

CAS No. : 
[1108743-60-7]    
MDL No. : 
MFCD28129099
Synonyms : N-(5-(3,5-Difluorobenzyl)-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-((tetrahydro-2H-pyran-4-yl)amino)benzamide; RXDX101; RXDX 101; RXDX-101; NMS E628; NMS-E628

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MGRequest QuoteBack Order Estimated to Ship on 01.20.2025
25MGRequest QuoteBack Order Estimated to Ship on 01.20.2025
100MGRequest QuoteBack Order Estimated to Ship on 01.20.2025

Entrectinib is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
C31H34F2N6O2 560.64
White solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Entrectinib is a potent and orally available Trk, ROS1, and ALK inhibitor; inhibits TrkA, TrkB, TrkC, ROS1 and ALK with IC50 values of 1, 3, 5, 12 and 7 nM, respectively.
References : Menichincheri M. et al.: J. Med. Chem., 59(7), 3392-3408, 2016; Ardini E. et al. Mol Cancer Ther., 15(4), 628-639, 2016; Rolfo C. et al. Expert Opin Investig Drugs. 24(11),1493-1500, 2015; Russo M. et al. Cancer Discov. 6(1), 36-44, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-2651

Product Name : Entrectinib

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!