[496775-62-3]    

MFCD22380664

Synonyms : 2-Aminoethanol hemi((Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate); (Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid bis(2-aminoethanol); Eltrombopag diethanolamine

Applications : Eltrombopag is a thrombopoietin-receptor agonist used to treat low blood platelet counts with chronic immune thrombocytopenia.

References : Erickson-Miller C. L. et al.: Stem Cells. 27(2), 424-430, 2009; Erickson-Miller C. L. et al.: Exp Hematol. 33(1), 85-93, 2005; McHutchison J. G. et al.: N. Engl. J. Med., 357(22), 2227-2236, 2007; Jenkins J. M. et al. Blood.109(11), 4739-4741, 2007; Saleh M. N. et al.: Blood. 121(3), 537-545, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.