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SI-3645

RN-486, >98% (HPLC)

CAS No. : 
[1242156-23-5]    
MDL No. : 
MFCD24682729
Synonyms : 6-Cyclopropyl-8-fluoro-2-(2-(hydroxymethyl)-3-(1-methyl-5-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)isoquinolin-1(2H)-one; RN486

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MGRequest QuoteBack Order Estimated to Ship on 12.05.2024
25MGRequest QuoteBack Order Estimated to Ship on 12.05.2024
100MGRequest QuoteBack Order Estimated to Ship on 12.05.2024
Chemical Properties
C35H35FN6O3 606.69
Off-white solid 257-259oC (lit.)
For Laboratory research use only, not for drug, household or other uses.
Applications : RN-486 is a potent and selective burton’s tyrosine kinase (BTK) inhibitor with an IC50 value of 4.0 nM.
References : Lou Y. et al.: J. Med. Chem., 58(1), 512-516, 2015.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-3645

Product Name : RN-486

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