SynInnova Laboratories Inc.

SI-3925

Dabrafenib mesylate, >98% (HPLC)

CAS No. :

[1195768-06-9]

MDL No. :

MFCD20922872

Synonyms : N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide mesylate; GSK-2118436A mesylate; GSK2118436 mesylate

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
25MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
100MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025

Chemical Properties
Mol. Formula : C₂₃H₂₀F₃N₅O₂S₂ . CH₃SO₂OH	Mol. Weight : 615.67
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Dabrafenib mesylate is an ATP-competitive inhibitor of Raf with IC50s of 5 nM and 0.6 nM for C-Raf and B-RafV600E, respectively.

References : Ding X. H. et al.: Bioorg. Med. Chem. 23(9), 1895-1922, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-3925

Product Name : Dabrafenib mesylate

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