SynInnova Laboratories Inc.

SI-3978

Ethyl 5-amino-1-(2-fluorobenzyl)-1H-pyrazole-3-carboxylate, 97%

CAS No. :

[256504-39-9]

MDL No. :

MFCD20268229

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
1G	120.00	- +	Back Order	Estimated to Ship on 12.05.2024
5G	500.00	- +	Back Order	Estimated to Ship on 12.05.2024

Chemical Properties
Mol. Formula : C₁₃H₁₄FN₃O₂	Mol. Weight : 263.27
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of Riociguat and related analogs, which is an oral stimulator of soluble guanylate cyclase (sGC) used in the treatment of pulmonary hypertension.

References : Ding X. H. et al.: Bioorg. Med. Chem. 23(9), 1895-1922, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-3978

Product Name : Ethyl 5-amino-1-(2-fluorobenzyl)-1H-pyrazole-3-carboxylate

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SL-3944	N-Desmethyl-riociguat
SL-3951	Ethyl 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbimidate
SL-3947	1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride
SL-3939	Riociguat impurity 6
SI-3981	1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide
SL-3945	N-Desmethyl-riociguat-d₃
SL-3942	Riociguat impurity 9
SL-3952	Riociguat impurity 11
SL-3936	Riociguat impurity 3
SI-3982	2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5,6-triamine
SL-3934	Riociguat impurity 1
SL-3941	Riociguat impurity 8