SynInnova Laboratories Inc.

SI-4332

Vemurafenib, >98% (HPLC)

CAS No. :

[918504-65-1]

MDL No. :

MFCD18074504

Synonyms : N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide; RO5185426; PLX4032; RG7204

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	60.00	- +	Back Order	Estimated to Ship on 11.30.2024
25MG	120.00	- +	Back Order	Estimated to Ship on 11.30.2024
50MG	220.00	- +	Back Order	Estimated to Ship on 11.30.2024
250MG	650.00	- +	Back Order	Estimated to Ship on 11.30.2024
500MG	1250.00	- +	Back Order	Estimated to Ship on 11.30.2024

Chemical Properties
Mol. Formula : C₂₃H₁₈ClF₂N₃O₃S	Mol. Weight : 489.92
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Vemurafenib is a novel and potent inhibitor of B-RafV600E with IC₅₀ of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold.

References : Ding H. X. et al.: Bioorg. Med. Chem. 21(11), 2795-2825, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-4332

Product Name : Vemurafenib

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