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SI-4564

Ponatinib, >98% (HPLC)

CAS No. : 
[943319-70-8]    
MDL No. : 
MFCD17215203
Synonyms : 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide; AP24534

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG90.00 Back Order Estimated to Ship on 12.18.2024
25MG180.00 Back Order Estimated to Ship on 12.18.2024
50MG350.00 Back Order Estimated to Ship on 12.18.2024
100MG650.00 Back Order Estimated to Ship on 12.18.2024
Chemical Properties
C29H27F3N6O 532.56
Pale yellow solid Not available
DMSO, MeOH
For Laboratory research use only, not for drug, household or other uses.
Applications : Ponatinib is a potent, orally available multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.
References : O'Hare T. et al.: Cancer Cell,16(5), 401-412, 2009; Gozgit J. M. et al.: Mol Cancer Ther.,10(6), 1028-1035, 2011; Uchida T. et al.: Exp Hematol. 42(5), 369-379, 2014.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-4564

Product Name : Ponatinib

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