SynInnova Laboratories Inc.

SI-4564

Ponatinib, >98% (HPLC)

CAS No. :

[943319-70-8]

MDL No. :

MFCD17215203

Synonyms : 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide; AP24534

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	90.00	- +	Back Order	Estimated to Ship on 01.20.2025
25MG	180.00	- +	Back Order	Estimated to Ship on 01.20.2025
50MG	350.00	- +	Back Order	Estimated to Ship on 01.20.2025
100MG	650.00	- +	Back Order	Estimated to Ship on 01.20.2025

Chemical Properties
Mol. Formula : C₂₉H₂₇F₃N₆O	Mol. Weight : 532.56
Appearance : Pale yellow solid	Melting Point : Not available
Solubility : DMSO, MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Ponatinib is a potent, orally available multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.

References : O'Hare T. et al.: Cancer Cell,16(5), 401-412, 2009; Gozgit J. M. et al.: Mol Cancer Ther.,10(6), 1028-1035, 2011; Uchida T. et al.: Exp Hematol. 42(5), 369-379, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-4564

Product Name : Ponatinib

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SI-4564

Ponatinib, >98% (HPLC)

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