SynInnova Laboratories Inc.

SI-4884

Danusertib, >98% (HPLC)

CAS No. :

[827318-97-8]

MDL No. :

MFCD12024692

Synonyms : (R)-N-(5-(2-Methoxy-2-phenylacetyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-4-(4-methylpiperazin-1-yl)benzamide; PHA-739358

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 03.30.2025
25MG	Request Quote	- +	Back Order	Estimated to Ship on 03.30.2025
100MG	Request Quote	- +	Back Order	Estimated to Ship on 03.30.2025

Chemical Properties
Mol. Formula : C₂₆H₃₀N₆O₃	Mol. Weight : 474.55
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Danusertib is an aurora kinase inhibitor for aurora A/B/C with IC₅₀ of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc.

References : Carpinelli P. et al.: Mol Cancer Ther., 12 Pt 1, 3158-3168, 2007; Fancelli D. et al.: J Med Chem., 49(24), 7247-7251, 2006; Gontarewicz A. et al. Blood 111(8), 4355-4364, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-4884

Product Name : Danusertib

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SI-4884

Danusertib, >98% (HPLC)

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