SynInnova Laboratories Inc.

SI-4889

SNS-314 mesylate, >98% (HPLC)

CAS No. :

[1146618-41-8]

MDL No. :

MFCD16621142

Synonyms : 1-(3-Chlorophenyl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea methanesulfonate; SNS314 mesylate

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 12.24.2024
25MG	Request Quote	- +	Back Order	Estimated to Ship on 12.24.2024
100MG	Request Quote	- +	Back Order	Estimated to Ship on 12.24.2024

Chemical Properties
Mol. Formula : C₁₈H₁₅ClN₆OS₂ . CH₃SO₂OH	Mol. Weight : 527.04
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SNS-314 mesylate is a potent and selective inhibitor of aurora A, aurora B and aurora C with IC₅₀ of 9 nM, 31 nM, and 3 nM, respectively. It is less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2.

References : Oslob J. D. et al.: Bioorg Med Chem Lett,, 18(17), 4880-4884, 2008; Vander Porten E. C. et al.: Mol Cancer Ther., 8(4), 930-939, 2009; Arbitrario J. P. et al.: Cancer Chemother Pharmacol., 65(4), 707-717, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-4889

Product Name : SNS-314 mesylate

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SI-4889

SNS-314 mesylate, >98% (HPLC)

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