SynInnova Laboratories Inc.

SI-5038

(R)-N-(3-(1-Hydroxy-2-((2-((3-methyl-1H-indazol-6-yl)oxy)ethyl)amino)ethyl)phenyl)methanesulfonamide hydrochloride, >98% (HPLC)

CAS No. :

[519158-31-7]

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	Request Quote	- +	Back Order	Estimated to Ship on 11.30.2024
25MG	Request Quote	- +	Back Order	Estimated to Ship on 11.30.2024
100MG	Request Quote	- +	Back Order	Estimated to Ship on 11.30.2024
250MG	Request Quote	- +	Back Order	Estimated to Ship on 11.30.2024
500MG	Request Quote	- +	Back Order	Estimated to Ship on 11.30.2024

Note: SI-5038 is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
Mol. Formula : C₁₉H₂₄N₄O₄S . HCl	Mol. Weight : 440.94
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a novel indazole derivative, and showed as human β3-adrenergic receptor (AR) agonistic activity (EC50 = 13 nM) and high selectivity (α1A/β3 = >769-fold). It was also inactive toward β1 and β2-ARs and showed dose dependent β3-AR mediated relaxation of marmoset urinary bladder smooth muscle, while it did not obviously affect heart rate or blood pressure (iv, 3 mg/kg) in anesthetized rats.

References : Wada Y. et al.: J. Med. Chem., 58(15), 6048-6057, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5038

Product Name : (R)-N-(3-(1-Hydroxy-2-((2-((3-methyl-1H-indazol-6-yl)oxy)ethyl)amino)ethyl)phenyl)methanesulfonamide hydrochloride

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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