SynInnova Laboratories Inc.

SI-5121

SX-517, >98% (HPLC)

CAS No. :

[1240494-13-6]

Synonyms : (2-(((5-((4-Fluorophenyl)carbamoyl)pyridin-2-yl)thio)methyl)phenyl)boronic acid

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
25MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
100MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
250MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
500MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025

Note: SX-517 is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
Mol. Formula : C₁₉H₁₆BFN₂O₃S	Mol. Weight : 382.22
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SX-517 is a potent noncompetitive boronic acid CXCR1/2 antagonist. SX-517 inhibited CXCL1-induced Ca(2+) flux (IC50 = 38 nM) in human PMNs but had no effect on the Ca(2+) flux induced by C5a, fMLF, or PAF. SX-517 is the first reported boronic acid chemokine antagonist and represents a novel pharmacophore for CXCR1/2 antagonism.

References : Schuler A. D. et al.: Bioorg Med Chem Lett., 25(18), 3793-3797, 2015;
Maeda D. Y. et al.: J. Med Chem., 57(20), 8378-97, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

To receive price and delivery information on larger quantities, please complete the form below and we will respond promptly.

If you login prior to completion of the form, your contact information will automatically populate.

Your request for quote will also be accepted by e-mail at sales@syninnova.com or Fax: +1 780 485 2963.

Product ID : SI-5121

Product Name : SX-517

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

Related Products

SI-5121

SX-517

SI-2766	6-Bromomethyl-pteridine-2,4-diamine
SI-1851	4-Cyano-N-(2-methylindazol-5-yl)benzenesulfonamide
SI-5121	SX-517
SI-5848	CCT-365623
SI-5364	Treprostinil palmitil
SI-3371	2-Fluoro-5-iodo-N,N-dimethylbenzamide
SA-604	Methyl 6-bromo-1H-indazole-3-carboxylate
SA-1285	2-(Dimethylamino)-5-(trifluoromethyl)benzaldehyde
SI-1233	LAS-195319
SI-1758	Ethyl 3-(((4-Methyl-5-(pyrimidin-4-yl)-4H-1,2,4-triazol-3-yl)-methyl)amino)benzoate
SI-3570	5-Bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine
SL-3184	N-Methoxyethyl erlotinib HCl

SI-5121

SX-517, >98% (HPLC)

Recently Viewed Products

Related Products