SynInnova Laboratories Inc.

SI-5190

Spebrutinib, >98% (HPLC)

CAS No. :

[1202757-89-8]

MDL No. :

MFCD25976876

Synonyms : N-(3-((5-Fluoro-2-((4-(2-methoxyethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide; AVL-292; CC-292

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	80.00	- +	In Stock	Estimated to Ship on 01.10.2025
50MG	280.00	- +	In Stock	Estimated to Ship on 01.10.2025
100MG	480.00	- +	In Stock	Estimated to Ship on 01.10.2025

Chemical Properties
Mol. Formula : C₂₂H₂₂FN₅O₃	Mol. Weight : 423.45
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Spebrutinib is a covalent, orally active, and highly selective BTK inhibitor with IC50 of <0.5 nM, displaying at least 1400-fold selectivity over the other kinases assayed. Spebrutinib was under clinical development for the treatment of rheumatoid arthritis (phase II) and B-cell Lymphoma (phase I).

References : Evans E. K et al. J. Pharmacol Exp Ther., 346(2), 219-28, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5190

Product Name : Spebrutinib

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Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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SI-5190

Spebrutinib, >98% (HPLC)

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