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SI-5190

Spebrutinib, >98% (HPLC)

CAS No. : 
[1202757-89-8]    
MDL No. : 
MFCD25976876
Synonyms : N-(3-((5-Fluoro-2-((4-(2-methoxyethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide; AVL-292; CC-292

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG80.00
-
+
In Stock Estimated to Ship on 12.09.2024
50MG280.00
-
+
In Stock Estimated to Ship on 12.09.2024
100MG480.00
-
+
In Stock Estimated to Ship on 12.09.2024
Chemical Properties
C22H22FN5O3 423.45
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Spebrutinib is a covalent, orally active, and highly selective BTK inhibitor with IC50 of <0.5 nM, displaying at least 1400-fold selectivity over the other kinases assayed. Spebrutinib was under clinical development for the treatment of rheumatoid arthritis (phase II) and B-cell Lymphoma (phase I).
References : Evans E. K et al. J. Pharmacol Exp Ther., 346(2), 219-28, 2013.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5190

Product Name : Spebrutinib

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