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SI-5224

Plazomicin, >98% (HPLC)

CAS No. : 
[1154757-24-0]    
Synonyms : (S)-4-Amino-N-((1R,2S,3S,4R,5S)-5-amino-4-(((2S,3R)-3-amino-6-(((2-hydroxyethyl)amino)methyl)-3,4-dihydro-2H-pyran-2-yl)oxy)-2-(((2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-3-hydroxycyclohexyl)-2-hydroxybutanamide

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MGRequest Quote
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Plazomicin is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!
Chemical Properties
C25H48N6O10 592.69
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Plazomicin is a next-generation aminoglycoside that has been designed as an antibiotic to avoid resistance through aminoglycoside-modifying enzymes. Plazomicin demonstrates high activity against the Enterobacteriaceae including extended spectrum beta lactamase and most carbapenemase producers, and can be useful in treating complicated urinary tract infections (cUTIs) and acute pyelonephritis.
References : Eljaaly K. et al.: Drugs 79(3), 243-269, 2019; Abdul-Mutakabbir J.C. et al.: Infect Dis Ther., 8(2), 155-170, 2019; Shaeer K. M. et al.: Pharmacotherapy 39(1), 77-93, 2019; McCarthy M. W. et al.: Drugs Today (Barc) 54(9), 513-518, 2018; Karaiskos I. et al.: Expert Opin Investig Drugs 24(11), 1501-11, 2015; Zhanel G. G. et al.: Expert Rev Anti Infect Ther., 10(4), 459-73, 2012.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5224

Product Name : Plazomicin

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Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

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