SynInnova Laboratories Inc.

SI-5261

Ivosidenib, >98% (HPLC)

CAS No. :

[1448347-49-6]

MDL No. :

MFCD29036964

Synonyms : (S)-N-((S)-1-(2-Chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide; AG-120

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	120.00	- +	In Stock	Estimated to Ship on 12.04.2024
25MG	180.00	- +	In Stock	Estimated to Ship on 12.04.2024
50MG	300.00	- +	In Stock	Estimated to Ship on 12.04.2024
100MG	500.00	- +	In Stock	Estimated to Ship on 12.04.2024
250MG	950.00	- +	In Stock	Estimated to Ship on 12.04.2024

Chemical Properties
Mol. Formula : C₂₈H₂₂ClF₃N₆O₃	Mol. Weight : 582.97
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ivosidenib is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib has the potential for AML therapy due to its acceptable safety profile and clinical activity.

References : Popovici-Muller J. et al.: ACS Med Chem Lett., 9(4), 300-305, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5261

Product Name : Ivosidenib

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