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SI-5291

MK-2206 dihydrochloride, >98% (HPLC)

CAS No. : 
[1032350-13-2]    
MDL No. : 
MFCD14584463
Synonyms : 8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG100.00 Back Order Estimated to Ship on 01.20.2025
25MG350.00 Back Order Estimated to Ship on 01.20.2025
50MG500.00 Back Order Estimated to Ship on 01.20.2025
100MG950.00 Back Order Estimated to Ship on 01.20.2025
Chemical Properties
C25H21N5O . 2HCl 480.39
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : MK-2206 dihydrochloride is a highly selective inhibitor of AKT1/2/3 with IC50 of 8 nM/12 nM/65 nM in cell-free assays, respectively; no inhibitory activities against 250 other protein kinases observed. MK-2206 dihydrochloride induces autophagy and apoptosis in cancer cells.
References : Hirai H. et al.: Mol Cancer Therapy, 9(7), 1956-1967, 2010; Cheng Y. et al.: Cancer Res, 71(7), 2654-2663, 2011.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5291

Product Name : MK-2206 dihydrochloride

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