SynInnova Laboratories Inc.

SI-5291

MK-2206 dihydrochloride, >98% (HPLC)

CAS No. :

[1032350-13-2]

MDL No. :

MFCD14584463

Synonyms : 8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	100.00	- +	Back Order	Estimated to Ship on 12.14.2024
25MG	350.00	- +	Back Order	Estimated to Ship on 12.14.2024
50MG	500.00	- +	Back Order	Estimated to Ship on 12.14.2024
100MG	950.00	- +	Back Order	Estimated to Ship on 12.14.2024

Chemical Properties
Mol. Formula : C₂₅H₂₁N₅O . 2HCl	Mol. Weight : 480.39
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : MK-2206 dihydrochloride is a highly selective inhibitor of AKT1/2/3 with IC50 of 8 nM/12 nM/65 nM in cell-free assays, respectively; no inhibitory activities against 250 other protein kinases observed. MK-2206 dihydrochloride induces autophagy and apoptosis in cancer cells.

References : Hirai H. et al.: Mol Cancer Therapy, 9(7), 1956-1967, 2010; Cheng Y. et al.: Cancer Res, 71(7), 2654-2663, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5291

Product Name : MK-2206 dihydrochloride

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SI-5291

MK-2206 dihydrochloride, >98% (HPLC)

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