SynInnova Laboratories Inc.

SI-5295

Tapotoclax, >98% (HPLC)

CAS No. :

[1883727-34-1]

Synonyms : (1S,11'R,12'S,16'S,16a'R,18a'R,E)-6-Chloro-16'-methoxy-11',12'-dimethyl-3,4,12',13',16',16a',17',18',18a',19'-decahydro-1'H,2H,3'H,11'H-spiro[naphthalene-1,2'-[5,7]ethenocyclobuta[i][1,4]oxazepino[3,4-f][1]thia[2,7]diazacyclohexadecin]-8'(9'H)-one 10',10'-dioxide; AMG-176

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
10MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
25MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
100MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025
250MG	Request Quote	- +	Back Order	Estimated to Ship on 01.20.2025

Note: Tapotoclax is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
Mol. Formula : C₃₃H₄₁ClN₂O₅S	Mol. Weight : 613.21
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Tapotoclax is a potent, selective and orally active MCL-1 inhibitor, with a Ki of 0.13 nM.

References : Caenepeel S. et al.: Cancer Discov., 8(12), 1582-1597, 2018; Garner T. P. et al.: Curr Opin Chem Biol., 39, 133-142, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

To receive price and delivery information on larger quantities, please complete the form below and we will respond promptly.

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Your request for quote will also be accepted by e-mail at sales@syninnova.com or Fax: +1 780 485 2963.

Product ID : SI-5295

Product Name : Tapotoclax

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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Tapotoclax, >98% (HPLC)

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