SynInnova Laboratories Inc.

SI-5303

Copanlisib-d₈, >98% (HPLC)

Isotopic Purity :

98 atom % D

CAS No. :

[2168537-35-5]

Synonyms : 2-Amino-N-(7-methoxy-8-(3-(morpholino-d₈)propoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)pyrimidine-5-carboxamide; BAY 80-6946-d₈

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 01.18.2025
10MG	Request Quote	- +	Back Order	Estimated to Ship on 01.18.2025
25MG	Request Quote	- +	Back Order	Estimated to Ship on 01.18.2025

Note: Copanlisib-d8 is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
Mol. Formula : C₂₃H₂₀D₈N₈O₄	Mol. Weight : 488.58
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Copanlisib-d8 is a deuterium labelled version analog of Copanlisib, which is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ, respectively. Copanlisib has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR. Copanlisib has superior antitumor activity.

References : Liu N. et al.: Mol Cancer Ther., 12(11), 2319-30, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Your request for quote will also be accepted by e-mail at sales@syninnova.com or Fax: +1 780 485 2963.

Product ID : SI-5303

Product Name : Copanlisib-d₈

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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SI-5303

Copanlisib-d8, >98% (HPLC)

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