SynInnova Laboratories Inc.

SI-5346

Inavolisib, >98% (HPLC)

CAS No. :

[2060571-02-8]

MDL No. :

MFCD31382124

Synonyms : (S)-2-((2-((S)-4-(Difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide; GDC-0077; RG6114

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 08.28.2024
10MG	Request Quote	- +	Back Order	Estimated to Ship on 08.28.2024
25MG	Request Quote	- +	Back Order	Estimated to Ship on 08.28.2024
50MG	Request Quote	- +	Back Order	Estimated to Ship on 08.28.2024
100MG	Request Quote	- +	Back Order	Estimated to Ship on 08.28.2024

Note: SI-5346 is not in stock, can be available through custom synthesis. The estimated lead-time is 8-10 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
Mol. Formula : C₁₈H₁₉F₂N₅O₄	Mol. Weight : 407.38
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Inavolisib is a potent, orally available, and selective PI3Kα inhibitor (IC50=0.038 nM). Inavolisib exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. Inavolisib is more selective for mutant versus wild-type PI3Kα.

References : Hong. R. et al.: Cancer Research, DOI: 10.1158/1538-7445.SABCS17-PD4-14

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Your request for quote will also be accepted by e-mail at sales@syninnova.com or Fax: +1 780 485 2963.

Product ID : SI-5346

Product Name : Inavolisib

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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SI-5346

Inavolisib, >98% (HPLC)

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