SynInnova Laboratories Inc.

SI-5373

Itacitinib adipate, >98% (HPLC)

CAS No. :

[1334302-63-4]

Synonyms : 3-(3-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(1-(3-fluoro-2-(trifluoromethyl)isonicotinoyl)piperidin-4-yl)azetidine-3-carbonitrile adipate

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	200.00	- +	Back Order	Estimated to Ship on 01.20.2025
25MG	350.00	- +	Back Order	Estimated to Ship on 01.20.2025
50MG	600.00	- +	Back Order	Estimated to Ship on 01.20.2025
100MG	950.00	- +	Back Order	Estimated to Ship on 01.20.2025
250MG	1850.00	- +	Back Order	Estimated to Ship on 01.20.2025

Chemical Properties
Mol. Formula : C₂₅H₂₁F₄N₉O . C₆H₁₀O₄	Mol. Weight : 685.64
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Itacitinib adipate is an orally active and selective inhibitor of JAK1 with an IC50 of 2 nM for human JAK1. Itacitinib shows >20-fold selectivity for JAK1 over JAK2 and >100-fold over JAK3 and TYK2; Itacitinib is used in the research of myelofibrosis.

References : Mascarenhas J. O. et al.: Haematologica., 102(2), 327-335, 2017; Lescoat A. et al.: Biochem Pharmacol., 178, 114103, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5373

Product Name : Itacitinib adipate

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SI-5373

Itacitinib adipate, >98% (HPLC)

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