[474544-83-7]    

Synonyms : 1-(3-(tert-Butyl)-4-methoxy-5-morpholinophenyl)-2-(5,6-diethoxy-7-fluoro-1-iminoisoindolin-2-yl)ethan-1-one hydrochloride; E5555 hydrochloride; ER-172594-00 hydrochloride

Applications : Atopaxar hydrochloride is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. Atopaxar hydrochloride, an antiplatelet agent, interferes with platelet signaling. Atopaxar hydrochloride can be used for the research of atherothrombotic disease.

References : Dockendorff C. et al.: ACS Med Chem Lett., 3(3), 232–237, 2012; Kogushi M. et al.: Eur. J. Pharmacol., 657(1-3), 131-137, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.