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SI-5421

Verubecestat, >98% (HPLC)

CAS No. : 
[1286770-55-5]    
MDL No. : 
MFCD28963974
Synonyms : (R)-N-(3-(3-Amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2H-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropicolinamide; MK-8931

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG90.00 Back Order Estimated to Ship on 12.22.2024
25MG200.00 Back Order Estimated to Ship on 12.22.2024
50MG350.00 Back Order Estimated to Ship on 12.22.2024
100MG500.00 Back Order Estimated to Ship on 12.22.2024
250MG1150.00 Back Order Estimated to Ship on 12.22.2024
Chemical Properties
C17H17F2N5O3S 409.41
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Verubecestat is an orally active, high-affinity BACE1 and BACE2 inhibitor with Ki values of 2.2 nM and 0.38 nM. Verubecestat effectively reduces Aβ40 and has the potential for alzheimer's disease.
References : Scott J. D. et al.: Med Chem., 59(23), 10435-10450, 2016; Yan R. et al.: Transl Neurodegener., 5, 13, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5421

Product Name : Verubecestat

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