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SI-5516

DBPR112, >98% (HPLC)

CAS No. : 
[1226549-49-0]    
Synonyms : (S)-4-(Dimethylamino)-N-(3-(4-((2-hydroxy-1-phenylethyl)amino)-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl)butanamide

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG450.00
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+
Back Order Estimated to Ship on 12.06.2024
10MG800.00
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+
Back Order Estimated to Ship on 12.06.2024
25MG1650.00
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+
Back Order Estimated to Ship on 12.06.2024
50MG2450.00
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Back Order Estimated to Ship on 12.06.2024
100MG3650.00
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+
Back Order Estimated to Ship on 12.06.2024
Chemical Properties
C32H33N5O3 535.65
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : DBPR112 is an orally active furanopyrimidine-based EGFR inhibitor with IC50s of 15 nM and 48 nM for EGFRWT and EGFRL858R/T790M, respectively. DBPR112 can occupy the ATP-binding site. DBPR112 has significant antitumor efficacy.
References : Lin S. Y. et al.: J. Med Chem., 62(22), 10108-10123, 2019.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5516

Product Name : DBPR112

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