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SI-5516

DBPR112, >98% (HPLC)

CAS No. : 
[1226549-49-0]    
Synonyms : (S)-4-(Dimethylamino)-N-(3-(4-((2-hydroxy-1-phenylethyl)amino)-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl)butanamide

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG450.00 Back Order Estimated to Ship on 01.20.2025
10MG800.00 Back Order Estimated to Ship on 01.20.2025
25MG1650.00 Back Order Estimated to Ship on 01.20.2025
50MG2450.00 Back Order Estimated to Ship on 01.20.2025
100MG3650.00 Back Order Estimated to Ship on 01.20.2025
Chemical Properties
C32H33N5O3 535.65
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : DBPR112 is an orally active furanopyrimidine-based EGFR inhibitor with IC50s of 15 nM and 48 nM for EGFRWT and EGFRL858R/T790M, respectively. DBPR112 can occupy the ATP-binding site. DBPR112 has significant antitumor efficacy.
References : Lin S. Y. et al.: J. Med Chem., 62(22), 10108-10123, 2019.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5516

Product Name : DBPR112

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