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SI-5528

CI-1040, >98% (HPLC)

CAS No. : 
[212631-79-3]    
MDL No. : 
MFCD02683961
Synonyms : 2-((2-Chloro-4-iodophenyl)amino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide; PD184352

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG70.00
-
+
Back Order Estimated to Ship on 01.19.2025
25MG150.00
-
+
Back Order Estimated to Ship on 01.19.2025
50MG220.00
-
+
Back Order Estimated to Ship on 01.19.2025
100MG350.00
-
+
Back Order Estimated to Ship on 01.19.2025
250MG550.00
-
+
Back Order Estimated to Ship on 01.19.2025
Chemical Properties
C17H14ClF2IN2O2 478.66
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : CI-1040 is an orally active, highly specific, small-molecule inhibitor of MEK with an IC50 of 17 nM for MEK1. CI-1040 is developing for potential treatment of breast cancer and other cancers.
References : Allen L. F. et al.: Semin Oncol., 30(5 Suppl 16), 105-16, 2003; Wei C. R. et al.: Eur Rev Med Pharmacol Sci., 20(10), 1961-8, 2016; Kramer B. W. et al.: BMC Cancer., 4, 24, 2004.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5528

Product Name : CI-1040

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