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SI-5625

BAY-985, >98% (HPLC)

CAS No. : 
[2409479-29-2]    
Synonyms : (R)-1-(4-(1-(2-((6-(6-(Dimethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-yl)amino)pyridin-4-yl)ethyl)piperazin-1-yl)-3,3,3-trifluoropropan-1-one

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG350.00 Back Order Estimated to Ship on 01.20.2025
10MG650.00 Back Order Estimated to Ship on 01.20.2025
25MG1250.00 Back Order Estimated to Ship on 01.20.2025
50MG1950.00 Back Order Estimated to Ship on 01.20.2025
100MG2850.00 Back Order Estimated to Ship on 01.20.2025
Chemical Properties
C27H30F3N9O 553.59
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : BAY-985 is a potent and highly selective TBK1/IKKε inhibitor. BAY-985 shows high potency toward TBK1 (IC50 = 2 nM, low ATP assay; 30 nM, high ATP assay) and IKKε(IC50 = 2 nM), as well as high potency in the mechanistic pIRF3 assay (IC50 = 74 nM), and an antiproliferative effect on SK-MEL-2 cells (IC50 = 900 nM).
References : Lefranc J. et al.: J. Med Chem., 63(2), 601-612, 2020.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5625

Product Name : BAY-985

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