SynInnova Laboratories Inc.

SI-5645

Merestinib, >98% (HPLC)

CAS No. :

[1206799-15-6]

MDL No. :

MFCD23160048

Synonyms : N-(3-Fluoro-4-((1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl)oxy)phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide; LY2801653

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	150.00	- +	Back Order	Estimated to Ship on 11.28.2024
25MG	350.00	- +	Back Order	Estimated to Ship on 11.28.2024
50MG	450.00	- +	Back Order	Estimated to Ship on 11.28.2024
100MG	650.00	- +	Back Order	Estimated to Ship on 11.28.2024

Chemical Properties
Mol. Formula : C₃₀H₂₂F₂N₆O₃	Mol. Weight : 552.54
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Merestinib is a potent, orally bioavailable c-Met inhibitor (Ki=2 nM) with antitumor activities. Merestinib also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK (IC50=10 nM), TEK (IC50=63 nM), ROS1, DDR1/2 (IC50=0.1/7 nM) and MKNK1/2 (IC50=7 nM).

References : Yan S. B. et al.: Invest New Drugs 31(4), 833-44, 2013; Barat S. et al.: Mol Carcinog 55(12), 2037-2050, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5645

Product Name : Merestinib

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