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SI-5660

GTS-21 dihydrochloride, >98% (HPLC)

CAS No. : 
[156223-05-1]    
MDL No. : 
MFCD00941364
Synonyms : (E)-3-(2,4-Dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine dihydrochloride

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG70.00
-
+
Back Order Estimated to Ship on 12.22.2024
25MG120.00
-
+
Back Order Estimated to Ship on 12.22.2024
50MG150.00
-
+
Back Order Estimated to Ship on 12.22.2024
100MG230.00
-
+
Back Order Estimated to Ship on 12.22.2024
250MG350.00
-
+
Back Order Estimated to Ship on 12.22.2024
Chemical Properties
C19H20N2O2 . 2HCl 381.30
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : GTS-21 dihydrochloride is a selective alpha7 nicotinic acetylcholine receptor (α7-nAChR) agonist with anti‑inflammatory and cognition‑enhancing activities. GTS-21 dihydrochloride is also a α4β2 (Ki=20 nM for humanα4β2) and 5-HT3A receptor (IC50=3.1 μM) antagonist.
References : Briggs C. A. et al.: Pharmacol Biochem Behav., 57(1-2), 231-241, 1997; Zhang R. et al.: J. Pharmacol Exp Ther., 317(3), 1276-1284, 2006; Mei Z. et al.: Oncol Rep., 40(4), 2287-2297, 2018.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5660

Product Name : GTS-21 dihydrochloride

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