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SI-5710

SB-674042, >98% (HPLC)

CAS No. : 
[483313-22-0]    
MDL No. : 
MFCD18251550
Synonyms : (S)-(5-(2-Fluorophenyl)-2-methylthiazol-4-yl)(2-((5-phenyl-1,3,4-oxadiazol-2-yl)methyl)pyrrolidin-1-yl)methanone

Price and Availability
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SB-674042 is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!
Chemical Properties
C24H21FN4O2S 448.52
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.
References : Alexander A. et al.: Biochemistry 51(15), 3178-3197, 2012; Malherbe P. et al.: Molecular Pharmacology 78(1), 81-93, 2010; Malherbe P. et al.: Molecular Pharmacology 76(3), 618-631, 2009; Ellis J. et al.: Journal of Biological Chemistry 281(50), 38812-38824, 2006; Langmead J. C. et al.: B. J. Pharmacol., 141(2), 340-346, 2004.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5710

Product Name : SB-674042

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!


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