[1143863-69-7]    

MFCD28970009

Synonyms : 3-(4-Fluorophenyl)chroman-4-one

Applications : KBU2046 is an oral, highly selective inhibitor of cell motility and cell invasion in vitro. KBU2046 binds chaperone heterocomplexes, selectively alters binding of client proteins that regulate motility, and lacks all of the hallmarks of classical Hsp90 inhibitors. KBU2046 inhibits cancer metastasis and prolongs life.

References : Xu L. et al.: Nat Commun., 9(1), 2454, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.