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SI-5868

Stavudine-d4, >98% (HPLC)

Isotopic Purity : 
98 atom % D
CAS No. : 
[1219803-67-4]    
Synonyms : 1-((2R,5S)-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl)-5-(methyl-d3)pyrimidine-2,4(1H,3H)-dione-6-d; d4T-d4

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MGRequest QuoteBack Order Estimated to Ship on 12.18.2024
10MGRequest QuoteBack Order Estimated to Ship on 12.18.2024
25MGRequest QuoteBack Order Estimated to Ship on 12.18.2024

Stavudine-d4 is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
C10H8D4N2O4 228.24
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Stavudine-d4 is the deuterium labelled version analog of Stavudine, which is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine has activity against HIV-1 and HIV-2. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis.
References : Moyle G. J. et al.: Antivir Ther., 2(4), 207-218, 1997; Riddler S. A. et al.: Antiviral Res., 27(3), 189-203, 1995; La Rosa F. et al.: J. Alzheimers Dis., 72(2), 401-412, 2019; Ferraresi R. et al.: FEBS Lett., 580(28-29), 6612-6616, 2006.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5868

Product Name : Stavudine-d4

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Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

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