[518048-05-0]    

MFCD10698872

Synonyms : N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide; MK-0518

Applications : Raltegravir is a potent integrase (IN) inhibitor, can be used to treat HIV infection.

References : Hare S. et al.: Proc Natl Acad Sci U S A 107(46), 20057-62, 2010;
Xu P. et al.: J. Neuroimmune Pharmacol., 12(4), 682-692, 2017; Hicks C. et al.: Clin Infect Dis., 48(7), 931-9, 2009; Moss D. M. et al.: Antimicrob Agents Chemother., 56(6), 3020-6, 2012; Hare S. et al.: Mol Pharmacol., 80(4), 565-72, 2011; Lewis M.G. et al.: Retrovirology. 7, 21, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.