[826-39-1]    

Synonyms : N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride

Applications : Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist that can treat various neuropsychiatric disorders. Mecamylamine hydrochloride is originally used as a ganglionic blocker in treating hypertension. Mecamylamine hydrochloride can easily crosses the blood-brain barrier.

References : Bacher I. et al.: Expert Opin Pharmacother., 10(16), 2709-21, 2009; Ostroumov K. et al.: Eur Biophys J. 37(4), 393-402, 2008; Rabenstein R. L. et al.: Psychopharmacology (Berl).189(3), 395-401, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.