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SL-1665

Tenovin-6, 98%

CAS No. : 
[1011557-82-6]    
MDL No. : 
MFCD11976906
Synonyms : N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG150.00 Back Order Estimated to Ship on 11.30.2024
50MG500.00 Back Order Estimated to Ship on 11.30.2024
100MG850.00 Back Order Estimated to Ship on 11.30.2024
500MG2850.00 Back Order Estimated to Ship on 11.30.2024
Chemical Properties
C19H30N4O3 362.47
Yellow solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Tenovin-6 is a water soluble inhibitor of SIRT1 and SIRT2, slightly inhibits HDAC8, and is also a potent activator of p53, with IC50s of 21 μM, 10 μM, and 67 μM for SirT1, SirT2, and SirT3, respectively.
References : Lain S. et al.: Cancer Cell. 13 (5), 454-463, 2008; Yuan H. et al.: Cell Death Dis. 8 (2), e2608, 2017; Yuan H. et al.: Oncotarget. 8 (9), 14912-14924, 2017; Dai W. et al.: Sci Rep. 6, 22622, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-1665

Product Name : Tenovin-6

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