[166403-66-3] of the unlabelled compound

Synonyms : Diphosphoric acid, anhydride with [[(1R)​-​2-​(6-​amino-​9H-​purin-​9-​yl)​-​1-​methylethoxy]​methyl]​phosphonic acid-d₆ (1:1); Diphosphoric acid, monoanhydride with [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid-d₆ (9CI); Diphosphoric acid, monoanhydride with [[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid-d₆; PMPApp-d₆

Applications : It is an isotopic analog of Tenofovir diphosphate or metabolite of Tenofovir, which is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.

References : Hazra. R. et al.: Antimicrob. Agents Chemother., 48, 124; 2004; Piketty. C. et al.: Antivir. Ther., 11, 213, 2006; Molto. J. et al.: Ther. Drug Monit., 29, 648, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.