[16401-99-3]    

MFCD01719331

Synonyms : 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-Indole-3-acetic acid ethyl ester; 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid ethyl ester; Ethyl 1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetate; Ethyl 1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetate; Indomethacin ethyl ester; Indomethacin impurity I

Applications : It is an analog of Indomethacin, which is a nonselective inhibitor of COX1 and COX2, used to reduce fever, pain, stiffness, and swelling.

References : Lopes R. S. et al.: J. Biosci., 41 (3), 381-394, 2016; Afroz S. et al.: J. Agri. Food Chem., 64 (37), 6950-6957, 2016; Qixiong Zhang, et al.: Chem. Mater., 29 (19), 8221-8238, 2017

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.