MFCD21363738

[99614-02-5] of the unlabelled compound

Synonyms : 9-Methyl-13C, d3-3-((2-methyl-1H-imidazol-1-yl)methyl)-2,3-dihydro-1H-carbazol-4(9H)-one; GR38032-13C, d3

Applications : Ondansetron-13C, d3 is a mixed labelled analog, which is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting)

References : Brown A. M. et al.: J. Physiol., 507 ( Pt 3), 653-665,1998; Barann M. et al.: Naunyn Schmiedebergs Arch Pharmacol., 362 (3), 255-265, 2000; Wildeboer K. M. et al.: Brain Res. 1300, 41-50, 2009; Khedhaier A. et al.: Chronobiol Int., 20 (6),1103-1116, 2003; Umathe S. N. et al.: Behav Pharmacol., 20(1), 78-83, 2009; Doggrell S. A. et al.: Expert Opin Drug Saf. 12 (3), 421-431, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.