SynInnova Laboratories Inc.

SL-2395

Sacubitril (RR) diastereomer, 98%

CAS No. :

[766480-48-2]

MDL No. :

MFCD28404716

Synonyms : 4-(((2R,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; (2R,4R)-Sacubitril diastereomer

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	580.00	- +	In Stock	Estimated to Ship on 12.06.2024
10MG	980.00	- +	In Stock	Estimated to Ship on 12.06.2024

Chemical Properties
Mol. Formula : C₂₄H₂₉NO₅	Mol. Weight : 411.49
Appearance : Off-white solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : It is a diastereomer [(2R,4R)-Sacubitril] of Sacubitril, a potent NEP inhibitor with an IC₅₀ of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696.

References : Ksander G. M. et al.: J. Med. Chem., 38 (10), 1689-700,1995; Voors A. A. et al.: Expert Opin Investig Drugs. 22 (8), 1041-1047, 2013; von Lueder T. G. et al. Circ Heart Fail. 8 (1), 71-78, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2395

Product Name : Sacubitril (RR) diastereomer

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Related Products

SL-3965	Sacubitril impurity 10
SL-3977	Sacubitril impurity 22
SL-3968	Sacubitril impurity 13
SL-3982	Sacubitril methyl ester
SL-3961	Sacubitril impurity 6
SL-3966	Sacubitril impurity 11
SL-3963	Sacubitril impurity 8
SL-3970	Sacubitril impurity 15
SL-3973	Sacubitril impurity 18
SL-2392	Sacubitrilat-d₄
SL-3975	Sacubitril impurity 20
SL-3971	Sacubitril impurity 16