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SL-2395 

Sacubitril (RR) diastereomer, 98%

CAS No. : 
[766480-48-2]    
MDL No. : 
MFCD28404716
Synonyms : 4-(((2R,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; (2R,4R)-Sacubitril diastereomer

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG580.00
-
+
In Stock Estimated to Ship on 11.18.2024
10MG980.00
-
+
In Stock Estimated to Ship on 11.18.2024
Chemical Properties
C24H29NO5 411.49
Off-white solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : It is a diastereomer [(2R,4R)-Sacubitril] of Sacubitril, a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696.
References : Ksander G. M. et al.: J. Med. Chem., 38 (10), 1689-700,1995; Voors A. A. et al.: Expert Opin Investig Drugs. 22 (8), 1041-1047, 2013; von Lueder T. G. et al. Circ Heart Fail. 8 (1), 71-78, 2015.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2395

Product Name : Sacubitril (RR) diastereomer

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