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SL-281

(E)-3-(4-methoxybenzylidene)-7-(6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyloxy)chroman-4-one, 96%

MDL No. : 
MFCD28144019

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG1280.00 Back Order Estimated to Ship on 02.02.2025
10MG2280.00 Back Order Estimated to Ship on 02.02.2025
Chemical Properties
C36H38N2O4 562.7
Oily liquid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Tacrine and (E)-7-hydroxy-3-(4-methoxybenzylidene) chroman-4-one hybrid proved to be the most potent against AChE and MAO-B with IC50 values of 67.9 nM and 0.401 μM, respectively. This compound was observed to cross the blood–brain barrier (BBB) in a parallel artificial membrane permeation assay for the BBB (PAMPA-BBB). It is an excellent multifunctional promising compound for development of novel drugs for Alzheimer’s disease (AD).
References : Sun Y. et. al.: Bioorganic & Medicinal Chemistry 21, 7406, 2013.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-281

Product Name : (E)-3-(4-methoxybenzylidene)-7-(6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyloxy)chroman-4-one

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