SynInnova Laboratories Inc.

SL-342

AG-1478-d₆ hydrochloride, >98% (CP)

Isotopic Purity :

99 atom % D

MDL No. :

MFCD28386061

Related CAS No. :

[170449-18-0] of the unlabelled compound

Synonyms : 6,7-Dimethoxy-d₆-4-(3'-chloroanilino)quinazoline hydrochloride; Tyrphostin AG-1478-d₆ hydrochloride; NSC 693255-d₆ hydrochloride

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	480.00	- +	In Stock	Available to Ship on 12.22.2024
25MG	1880.00	- +	In Stock	Available to Ship on 12.22.2024

Chemical Properties
Mol. Formula : C₁₆H₈D₆ClN₃O₂ . HCl	Mol. Weight : 358.25
Appearance : Off-white solid	Melting Point : 258-260^oC
Solubility : DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is the deuterium labelled analog of AG-1478 hydrochloride. A selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV).

References : Jo M. et. al.: J. Bio. Chem., 275(12), 8806, 2000; Bojko A. et al.: Folia Histochem Cytobiol., 50(2), 186-195, 2012; Li W. et al.: Sci Rep., 6, 24580, 2016; Akhtar S. et al.: PLoS One 10(7), e0132215, 2015; Dorobantu C. M. et al.: Antimicrob Agents Chemother., 60(10), 6402-6, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-342

Product Name : AG-1478-d₆ hydrochloride

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Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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