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SL-342 

AG-1478-d6 hydrochloride, >98% (CP)

Isotopic Purity : 
99 atom % D
MDL No. : 
MFCD28386061
Related CAS No. : 
[170449-18-0] of the unlabelled compound
Synonyms : 6,7-Dimethoxy-d6-4-(3'-chloroanilino)quinazoline hydrochloride; Tyrphostin AG-1478-d6 hydrochloride; NSC 693255-d6 hydrochloride

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG480.00 In Stock Available to Ship on 11.20.2024
25MG1880.00 In Stock Available to Ship on 11.20.2024
Chemical Properties
C16H8D6ClN3O2 . HCl 358.25
Off-white solid 258-260oC
DMSO
For Laboratory research use only, not for drug, household or other uses.
Applications : This is the deuterium labelled analog of AG-1478 hydrochloride. A selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV).
References : Jo M. et. al.: J. Bio. Chem., 275(12), 8806, 2000; Bojko A. et al.: Folia Histochem Cytobiol., 50(2), 186-195, 2012; Li W. et al.: Sci Rep., 6, 24580, 2016; Akhtar S. et al.: PLoS One 10(7), e0132215, 2015; Dorobantu C. M. et al.: Antimicrob Agents Chemother., 60(10), 6402-6, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-342

Product Name : AG-1478-d6 hydrochloride

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