SynInnova Laboratories Inc.

SL-3520

Macitentan impurity 1, 98%

CAS No. :

[1433875-21-8]

Synonyms : 5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinamine; Despropylaminosulfonyl-macitentan ; ACT 080803

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	300.00	- +	Back Order	Estimated to Ship on 01.25.2025
10MG	580.00	- +	Back Order	Estimated to Ship on 01.25.2025
25MG	1280.00	- +	Back Order	Estimated to Ship on 01.25.2025

Chemical Properties
Mol. Formula : C₁₆H₁₃Br₂N₅O₂	Mol. Weight : 467.11
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Macitentan (Macitentan impurity 1), which is an orally active, non-peptide endothelin receptor antagonist for the treatment of idiopathic pulmonary fibrosis and pulmonary arterial hypertension.

References : Iglarz M. et al. J. Pharmacol Exp Ther., 327(3), 736-745, 2008; Sen S. et al.: Life Sci., 91(13-14), 658-668, 2012; Kim S. J. et al.: Neoplasia., 13(2), 167-179, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3520

Product Name : Macitentan impurity 1

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Related Products

SL-3525	Macitentan impurity 7
SL-2719	Macitentan-d₄
SL-3519	N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N’-propylsulfamide
SL-3521	Macitentan impurity 2
SI-3964	O-Desbromo-pyrimidinyl-macitentan
SL-3517	N-Despropyl-macitentan-d₄
SL-3534	Macitentan impurity 14
SL-3529	Macitentan impurity 11
SL-3526	Macitentan impurity 8
SL-3536	Macitentan impurity 16
SL-3527	Macitentan impurity 9
SL-3535	Macitentan impurity 15

SL-3520	Macitentan impurity 1
SI-3558	4-(2-((6-(4-Methoxyphenoxy)pyrimidin-4-yl)(methyl)amino) ethoxy)benzaldehyde
SL-6054	T-705RTP
SL-7220	Formoterol EP impurity A
sl-392	Capsaicin-d₃
SL-4325	N-Nitroso-desloratadine
SI-685	Methyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate
SL-7225	Formoterol EP impurity E
SA-148	2-Cyanopyridine-5-boronic acid pinacol ester
SL-5901	(3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methanol
SL-7228	Formoterol EP impurity H
SL-7785	N-Amino eliglustat

SL-3520

Macitentan impurity 1, 98%

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