SynInnova Laboratories Inc.

SL-3585

N-(2-Hydroxyethyl)-6-oxo-1,6-dihydropyridine-3-carboxamide, 98%

CAS No. :

[896133-95-2]

Synonyms : Nicorandil impurity 5

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
25MG	150.00	- +	Back Order	Estimated to Ship on 12.03.2024
250MG	1200.00	- +	Back Order	Estimated to Ship on 12.03.2024

Chemical Properties
Mol. Formula : C₈H₁₀N₂O₃	Mol. Weight : 182.18
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : N-(2-Hydroxyethyl)-6-oxo-1,6-dihydropyridine-3-carboxamide is an impurity of Nicorandil (Nicorandil impurity 5), which is a potassium channel activator, and stimulates guanylate cyclase to increase formation of cyclic GMP (cGMP), used to treat angina.

References : Sato T. et al. J. Am. Coll. Cardiol., 35(2), 514-518, 2000; Akao M.et al.: J. Am. Coll. Cardiol., 40(4), 803-810, 2002; Szczepanik A. M. et al.: J. Pharmacol Exp Ther., 278(2), 913-920, 1996; Teshima Y. et al.: Brain Res., 990(1-2), 45-50, 2003; Sathish V. et al.: Mol Cell Biochem., 243(1-2), 133-138, 2003.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3585

Product Name : N-(2-Hydroxyethyl)-6-oxo-1,6-dihydropyridine-3-carboxamide

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