SynInnova Laboratories Inc.

SL-371

Vandetanib N-Oxide, 97%

CAS No. :

[1797030-22-8]

MDL No. :

MFCD28343977

Synonyms : 4-(((4-((4-Bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-yl)oxy)methyl)-1-methylpiperidine 1-oxide

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	1280.00	- +	Back Order	Estimated to Ship on 02.02.2025
10MG	1980.00	- +	Back Order	Estimated to Ship on 02.02.2025
25MG	3980.00	- +	Back Order	Estimated to Ship on 02.02.2025

Chemical Properties
Mol. Formula : C₂₂H₂₄BrFN₄O₃	Mol. Weight : 491.35
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Vandetanib N-Oxide is the second major metabolite of vandetanib formed during the metabolism of vandetanib via flavin-containing monooxygenase (FMO) polymorphisms FMO1 and FMO3. Exposure to vandetanib N-oxide was very low compared with that of vandetanib and increased exposure to vandetanib N-oxide led to severe hepatic impairment.

References : GiangThy N. T. Am. J. Health Syst. Pharm. 70(10), 849, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-371

Product Name : Vandetanib N-Oxide

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SL-371

Vandetanib N-Oxide, 97%

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