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MFCD00467154

Synonyms : 6-(Biotinamidocaproylamido)caprice acid N-hydroxysuccinimide ester; N-Succinimidyl N-[6-(biotinylamino)caproyl]-6-aminocaproate; Biotin-X-X-NHS

Applications : Biotinylation reagent incorporating an extended C-atom spacer can reduce steric hindrance in binding avidin or streptavidin to some biotinylated compounds and increase sensitivity for detection. Typically coupled to primary amine in the pH range 6.5-8.5. Biotinylated satellite probes are useful in sequence-specific microscopic visualization of DNA methylation status at satellite repeats in individual cell nuclei and chromosomes.

References : Yufeng Li.et.al.: Nucleic Acids Research 41(19) e186, 2-9, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.