[887628-40-2]    

MFCD05865045

Synonyms : 2,5-Dioxopyrrolidin-1-yl 11-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl) pentanamido)undecanoate; Biotin-SLC-NHSEster

Applications : N-Hydroxysulfosuccinimide (NHS) esters of biotin are the most popular type of biotinylation reagents and NHS-activated biotins react efficiently with primary amino groups (-NH2) in alkaline buffers to form stable amide bonds. Extended chain increases avidin or streptavidinbinding and reduces potential steric hindrance of biotin and conjugated molecule.

References : Hofman K. et.al.: Biochemistry 21, 978, 1982.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.