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Synonyms : 4-(5-(m-Tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzene-d4-sulfonamide; Celecoxib-d4 USP related compound A

Applications : This is a deuterium labelled impurity of Celecoxib (Celecoxib-d4 EP impurity A). A COX-2 selective nonsteroidal anti-inflammatory drug. It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis.

References : Penning T. D. et al.: J. Med. Chem., 40(9), 1347-1365, 1997; Liu D. B. et al.: Acta Pharmacol Sin., 33(5), 682-690, 2012; Hunter N. R. et al.: Int J Radiat Oncol Biol Phys., 85(2), 472-476, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.